Shope Fibroma Virus (Rabbit Fibroma)

Creative Biolabs has been deeply involved in the life science field for over a decade and is committed to providing a one-stop solution in terms of reliable virus products and virus-related drug development. Monkeypox virus infection causes outbreaks in humans worldwide and leads to cutaneous and systemic diseases and in some cases death. Poxvirus is a DNA virus with multiple branches and has the potential to infect animals and/or humans. Therefore, some other poxviruses, such as the Shope fibroma virus (rabbit fibroma), are also of concern.

Fig.1 Rabbit.

Background of Shope Fibroma Virus (Rabbit Fibroma)

The Shope fibroma virus is a contagious poxvirus belonging to the genus Leporipoxvirus, which is intimately associated with the myxoma virus that causes fatal myxomatosis in rabbits. The Shope fibroma virus was first found in the USA in 1931 and is now prevalent around east of the Mississippi River in the USA. The Shope fibroma virus is transmitted via mechanical vectors such as mosquitoes, fleas, and other biting insects and infects rabbits, hares, and gray squirrels. Rabbit fibromatosis is characterized by several small, firm pinkish-red, and spherical tumors on the legs, feet, and head of rabbits, which rarely lead to alopecia, systematic diseases, and skin ulceration and regress after 6 months of infection. Younger populations of rabbits are more susceptible to infection with Shope fibromas. Although rabbits are able to develop antibodies and be immune to reinfection following the regression of a fibroma, the infection affects the animal’s well-being by hindering locomotion and feeding. Currently, there are no effective treatment regimens for Shope fibromas.

Shope Fibroma Virus (Rabbit Fibroma) Services at Creative Biolabs

Although the Shope fibroma virus can be automatically eliminated by the immune system of infected animals, the formation of the Shope fibroma may have negative impacts on animal well-being and animal fur. Creative Biolabs is devoted to providing a full range of viral products and professional solutions equipped with advanced high-throughput screening, artificial intelligence, and in vitro and in vivo platforms. Our services allow our customers a deeper understanding of the crucial steps of the infectious virus lifecycle, including cell attachment and entry, gene expression, uncoating of the viral core, replication, and viral assembly. Our experienced team helps you in designing your customized anti-viral agent discovery solutions. If you are interested in our Shope fibroma virus services, please do not hesitate to contact us.