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Monkeypox is an infectious disease. Monkeypox virus, an orthopoxvirus zoonotic virus, is the disease-causing agent. Fever, enlarged lymph nodes, and a rash that develops blisters before crusting over are all symptoms. Typically, symptoms last between two and four weeks. It has been discovered that not all outbreaks exhibit the typical presentation of fever and muscle pains followed by enlarged glands and lesions all developing at the same time.