We DO NOT PROVIDE ANY PRODUCTS OR SERVICES DIRECTLY TO PATIENTS. All of our products are for Research Use Only (RUO), NOT intended for diagnostic, therapeutic, or clinical use.
Monkeypox, caused by the monkeypox virus (MPXV), has emerged as a global concern in recent years due to its potential for zoonotic transmission and outbreaks among humans. A critical focus in understanding and combating Monkeypox lies in the characterization of viral proteins, such as A33R. This protein is a key component of the virus, playing vital roles in its replication and pathogenesis. Creative Biolabs, leveraging decades of expertise in antibody development, offers specialized services for the generation and optimization of A33R-specific antibodies to support advanced research and diagnostic applications.
At Creative Biolabs, we provide comprehensive and customizable A33R-specific antibody development services, ensuring precision and efficiency. Our services are designed to meet diverse research needs and include the following:
The first step in antibody development is the careful design of the antigen. Our team utilizes advanced bioinformatics tools to identify immunogenic epitopes of A33R, ensuring the generation of high-affinity antibodies. We also provide synthetic peptide and recombinant protein production services to create robust antigens for immunization and screening.
We employs state-of-the-art hybridoma technology to produce monoclonal antibodies. This includes:
Our phage display platforms enable the development of fully human or humanized monoclonal antibodies. This method involves:
To enhance antibody performance, we offer engineering services such as:
We provide scalable antibody production in various host systems, including mammalian cells, bacteria, and yeast. Rigorous validation processes, including ELISA, Western blot, and flow cytometry, ensure the functionality and specificity of the antibodies.
A33R is an envelope glycoprotein of Monkeypox virus and plays a pivotal role in the viral lifecycle.
A33R is primarily involved in the formation and release of extracellular enveloped virus (EEV) particles. It facilitates the transport of virions to the cell surface, enhancing viral dissemination within the host. This process is critical for the efficient spread of infection and the establishment of systemic disease.
A33R is also implicated in immune evasion. By modulating host immune responses, it allows the virus to evade detection and destruction by the host's immune system. This property makes A33R a crucial target for research aimed at understanding viral immunopathology and designing effective diagnostic tools.
| Cat# | Product Name | Target | Antibody Isotype | Species Reactivity | Applications |
|---|---|---|---|---|---|
| MPYF-0822-YF15 | Anti-Vaccinia Virus A33R Monoclonal Antibody (MP-X15) | A33R | Mouse IgG2a, kappa | Vaccinia Virus | Neut, ELISA |
| MPYF-0822-YF16 | Anti-Vaccinia Virus A33R Monoclonal Antibody (MP-X16) | A33R | Mouse IgG2b | Vaccinia Virus | Neut, ELISA |
| MPYF-1122-KX1620 | Anti-Squirrel Parapoxvirus A33R Monoclonal Antibody (MP-K2420) | A33R | Mouse IgG | Squirrel Parapoxvirus | WB (Other applications need to be tested) |
| MPYF-0822-YF112 | Anti-Monkeypox Virus A33R Monoclonal Antibody (MP-W77) | A33R | Mouse IgG | Monkeypox Virus | WB (Other applications need to be tested) |
| MPYF-0822-YF14 | Anti-Vaccinia Virus A33R Monoclonal Antibody (MP-X14) | A33R | Mouse IgG2a, kappa | Vaccinia Virus | Neut, ELISA |
| MPYF-1022-KX1359 | Anti-Vaccinia Virus (Smallpox Vaccine) A33R Monoclonal Antibody (MP-K1293) | A33R | Mouse IgG | Vaccinia Virus (Smallpox Vaccine) | WB (Other applications need to be tested) |
| Cat# | Product Name | Usage |
|---|---|---|
| MPYF-0722-KX1696 | Monkeypox Virus A33R IgG ELISA Kit (RUO) | RUO |
| MPYF-0722-KX1697 | Monkeypox Virus A33R IgM ELISA Kit (RUO) | RUO |
| MPYF-0722-KX1695 | Monkeypox Virus A33R IgA ELISA Kit (RUO) | RUO |
| Cat# | Product Name | Species | Target |
|---|---|---|---|
| MPYF-0722-KX1448 | Monkeypox virus, A33R-F | Monkeypox virus | A33R |
| MPYF-0722-KX1639 | Monkeypox virus, A33R-R | Monkeypox virus | A33R |
| Cat# | Product Name | Species | Target |
|---|---|---|---|
| MPYF-0722-KX1257 | Magic™ Monkeypox virus A33R Expression Plasmid | Monkeypox virus | A33R |
Creative Biolabs integrates cutting-edge platforms and technologies to deliver unparalleled antibody development services:
Rapid identification of high-affinity antibodies using automated systems.
Enhanced precision in antibody generation and epitope mapping.
Scalable and high-yield production of recombinant antibodies.
Deep characterization of antibody repertoires.
A33R-specific antibodies have a broad range of applications, including:
Creative Biolabs is a trusted partner in antibody development, offering:
Creative Biolabs specializes in monoclonal, polyclonal, recombinant, and humanized antibodies to suit various research needs.
Yes, Creative Biolabs offers comprehensive antibody screening services tailored to your specific research needs. Whether you're looking for antibodies suitable for Western blot, ELISA, immunohistochemistry, or flow cytometry, we can provide solutions optimized for each application.
Yes, Creative Biolabs offers epitope mapping services to identify the exact binding sites of your A33R antibodies. This can help improve the specificity and efficiency of your research, particularly for diagnostic assay development.
Creative Biolabs typically uses mice, rabbits, or guinea pigs for antibody generation, based on your project requirements. We can also tailor immunization protocols to specific animal models to meet your experimental needs.
We DO NOT PROVIDE ANY PRODUCTS OR SERVICES DIRECTLY TO PATIENTS. All of our products are for Research Use Only (RUO), NOT intended for diagnostic, therapeutic, or clinical use.