DNA Vaccine-Based Anti-monkeypox Drug Discovery Solutions

Creative Biolabs is a world-leading service provider with a good reputation. After decades of accumulation, we have accumulated rich experience in the field of monkeypox (MPX) virus research. At Creative Biolabs, our dedicated experts have built a reputation for delivering first class DNA vaccine-based anti-MPX drug discovery service with fast turnaround times.

Introduction of MPX

MPX is a rare viral disease caused by the MPX virus. MPX virus is a member of the Orthopoxvirus genus of the Poxviridae family. MPX is a zoonotic disease that is spread through close contact with an infected person or animal or material contaminated with the virus. MPX typically presents clinically as fever, rash, and swollen lymph nodes, and can lead to a range of medical complications. The symptoms of MPX are similar to those of smallpox. The pathogenicity of smallpox and monkeypox in humans is different. Smallpox is highly transmissible in humans with high mortality whereas monkeypox is less efficient in spreading and has low mortality. Generally, MPX does not require treatment.

Fig.1 Skin and soft tissue manifestations of MPX. (Adler, 2022)

DNA Vaccine Strategies for MPX

Prevention is an effective medical intervention, and vaccines are the most representative example. DNA vaccination holds great promise. Protective DNA vaccines are an alternative to live virus vaccines currently used to prevent smallpox infection, which could be an important tool in the control of poxviruses. Compared with live virus vaccines, DNA vaccines have many advantages, such as safety and simplicity of manufacture. For years, scientists have worked to maximize these advantages in order to establish DNA vaccines as a core component of preventive medicine. DNA vaccines have been reported to play a crucial role in protecting non-human primates from any MPX-related disease.

DNA Vaccine-based Drug Discovery Services

At present, the treatment of MPX virus infection remains a difficult task. Fortunately, scientists have discovered that DNA vaccines and drugs that prevent smallpox have great potential in preventing MPX virus infection. In addition, the genetic similarity between MPX and variola virus provides a theoretical basis for further research on vaccines and anti-MPX virus drugs. At Creative Biolabs, we focus on providing suitable models, rational testing methods as well as necessary immunological tools. With extensive experience and advanced platforms, we are confident to help our customers worldwide select the most promising vaccine candidates to advance your DNA vaccine discovery program.

As a leader in the field of vaccine development, Creative Biolabs has always been focused on providing customers with the most satisfactory one-stop service for MPX-related DNA vaccine-based drug discovery. If you are interested in developing the anti-MPX vaccine and monkeypox research products, please feel free to contact us for more details.

Reference

1. Adler, H.; etal. Clinical features and management of human monkeypox: a retrospective observational study in the UK. The Lancet Infectious Diseases. 2022.