Monkeypox virus, B14R-R(MPYF-0722-KX1671)

Target

B14R

Full Name

IL-beta-binding protein

Alternative Names

MPXVgp175; B14R; IL-beta-binding protein; binds to cytokines that participate in the regulation of immune responses (interleukin beta) to mediate host immune evasion; similar to vaccinia virus strain Copenhagen B16R; has ATP-binding domain; transfers the gamma phosphate from ATP to one or more amino acid residues in a protein substrate; the poxviridae are enveloped unsegmented dsDNA viruses; unlike many dsDNA viruses that replicate in the host nucleus poxviruses encode their own replication machinery and therefore replicate in the cytoplasm; viral genes are expressed in a bi-phasic manner with early genes genes encoding non-structural proteins involved in genome replication and late genes encoding the viral structural proteins

Gene ID

UniProt ID