This product is a made-to-order Monkeypox virus B14R expression plasmid. The product is for research use only and is not approved for use in humans or in clinical diagnosis.
Expression vector or lentiviral vector
Based on vector
Based on specific requirements
MPXVgp175; B14R; IL-beta-binding protein; binds to cytokines that participate in the regulation of immune responses (interleukin beta) to mediate host immune evasion; similar to vaccinia virus strain Copenhagen B16R; has ATP-binding domain; transfers the gamma phosphate from ATP to one or more amino acid residues in a protein substrate; the poxviridae are enveloped unsegmented dsDNA viruses; unlike many dsDNA viruses that replicate in the host nucleus poxviruses encode their own replication machinery and therefore replicate in the cytoplasm; viral genes are expressed in a bi-phasic manner with early genes genes encoding non-structural proteins involved in genome replication and late genes encoding the viral structural proteins