Monkeypox virus, P2L-R(MPYF-0722-KX1520)

Target

P2L

Full Name

Putative alpha aminitin-sensitive protein

Alternative Names

MPXVgp024; P2L; putative alpha aminitin-sensitive protein; mutations in this protein may confer resistance to alpha-amanitin, an inhibitor of RNA polymerase II; similar to vaccinia virus strain copenhagen N2L and lumpy skin disease virus 009; The poxviridae are enveloped unsegmented dsDNA viruses; unlike many dsDNA viruses that replicate in the host nucleus poxviruses encode their own replication machinery and therefore replicate in the cytoplasm; viral genes are expressed in a bi-phasic manner with early genes encoding non-structural proteins involved in genome replication and late genes encoding the viral structural proteins

Gene ID

UniProt ID