Monkeypox virus, C1L-R(MPYF-0722-KX1523)

Target

C1L

Full Name

Ankyrin-like protein

Alternative Names

MPXVgp027; C1L; ankyrin-like protein; similar to vaccinia virus strain Copenhagen K1L; although the function of the ankyrin-like protein is not completely understood, it is highly conserved throughout the Orthopoxvirus genus; it may be critical for overcoming host immune responses; the ankyrin-like protein of the modified vaccinia virus ankara interacts with Skp1a, a member of the Skp1a-Cullin-1-F-box (SCF) ubiquitin ligase complex; The poxviridae are enveloped unsegmented dsDNA viruses; unlike many dsDNA viruses that replicate in the host nucleus poxviruses encode their own replication machinery and therefore replicate in the cytoplasm; viral genes are expressed in a bi-phasic manner with early genes genes encoding non-structural proteins involved in genome replication and late genes encoding the viral structural proteins

Gene ID

UniProt ID