Monkeypox virus, O1L-R(MPYF-0722-KX1521)

Target

O1L

Full Name

Ankyin-like protein

Alternative Names

MPXVgp025; O1L; ankyin-like protein; although the function of the ankyrin-like proteins are not completely understood, they are highly conserved throughout the Orthopoxvirus genus; Ankyrin repeats are tandemly repeated modules of approximately 33 amino acids; there are no known specific sequence or structural motifs which are recognized by the module; the ankyrin-like protein of the modified vaccinia virus ankara interacts with Skp1a, a member of the Skp1a-Cullin-1-F-box (SCF) ubiquitin ligase complex; the poxviridae are enveloped unsegmented dsDNA viruses; unlike many dsDNA viruses that replicate in the host nucleus poxviruses encode their own replication machinery and therefore replicate in the cytoplasm; viral genes are expressed in a bi-phasic manner with early genes encoding non-structural proteins involved in genome replication and late genes encoding the viral structural proteins

Gene ID

UniProt ID