Monkeypox virus, C9L-R(MPYF-0722-KX1531)

Target

C9L

Full Name

Kelch-like protein

Alternative Names

MPXVgp035; C9L; Kelch-like protein; intracellular protein expressed in late infection stages; may be involved in remodelling and stabilization of the host cytoskeleton; contains a BTB/POZ domain which mediates dimerisation; similar to Vaccinia virus Copenhagen F3L; the poxviridae are enveloped unsegmented dsDNA viruses; unlike many dsDNA viruses that replicate in the host nucleus poxviruses encode their own replication machinery and therefore replicate in the cytoplasm; viral genes are expressed in a bi-phasic manner with early genes genes encoding non-structural proteins involved in genome replication and late genes encoding the viral structural proteins

Gene ID

UniProt ID