Monkeypox virus, C18L-F(MPYF-0722-KX1349)

Target

C18L

Full Name

EEV maturation protein

Alternative Names

MPXVgp044; C18L; EEV maturation protein; similar to vaccinia virus strain Copenhagen F12L; facilitates the transport of intracellular viral particles to the cell membrane; in its absence particles are assembled but remain intracellular and do not traffic to cell membrane; The poxviridae are enveloped unsegmented dsDNA viruses; unlike many dsDNA viruses that replicate in the host nucleus poxviruses encode their own replication machinery and therefore replicate in the cytoplasm; viral genes are expressed in a bi-phasic manner with early genes encoding non-structural proteins involved in genome replication and late genes encoding the viral structural proteins

Gene ID

UniProt ID