Anti-Orthopoxviruses A27 Monoclonal Antibody (MP-X11) (Mouse IgG2a/Human IgG1, Kappa)(MPYF-0822-YF11)
This antibody recognizes Orthopoxviruses A27. The isotype is Mouse IgG2a/Human IgG1, Kappa. It can be used in applications: Immunogold electron microscopy; IP; WB; ELISA; FC; IF.
Product Description
Species Reactivity
Orthopoxviruses
Cross Reactivity
Monkeypox Virus
Specificity
This antibody identifies ECTV and several other orthopoxviruses. Its epitope is localized on a tetrapeptide at the VACV homologue A27. Ectromelia virus (ECTV), belonging to the Poxviridae family and Orthopoxvirus genus, causes mousepox. Orthopoxviruses are linked to monkeypox.
Immunogen
Sucrose-gradient purified Ectromelia virus (ECTV) Strain Munich 1
Antibody Isotype
Mouse IgG2a/Human IgG1, Kappa
Clonality
Monoclonal Antibody
Purification
Protein A affinity purified
Applications
Immunogold electron microscopy; IP; WB; ELISA; FC; IF
Application Notes
This antibody is recommended for detecting and analyzing Orthopox viruses, particularly Ectromelia virus (ECTV). The mouse IgG2a version of this clone (EM-5B1/2G6) was also used to create an ELISA capture assay as a capture antibody, making it an excellent candidate for developing an anti-orthopox virus detection assay.
Buffer
PBS with 0.02% Proclin 300
Preservative
0.02% Proclin 300
Storage
Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Target
Introduction
The Monkeypox virus (MPV) is a zoonotic virus with double-stranded DNA, belonging to the Orthopoxvirus genus in the Poxviridae family. It induces a disease that shares similarities with smallpox, characterized by a milder rash and lower mortality rate. This virus can infect both humans and animals.
Alternative Names
Orthopoxvirus; Monkeypox; Ectromelia virus; ECTV; ECTV-5B1/2G6; EM-5B1/2G6; Mab EX-uUl 5BA 05.11.20
Warnings
For Research Use Only. Not for Clinical Use or Diagnostic Use.
Datasheet