Monkeypox virus, L3R-F(MPYF-0722-KX1392)

Target

L3R

Full Name

Poly(A) polymerase small subunit

Alternative Names

MPXVgp087; L3R; poly(A) polymerase small subunit; methylates the ribose 2' OH group of the first transcribed nucleotide; structure has been solved (PDB: 2ga9);The poxviridae are enveloped unsegmented dsDNA viruses; unlike many dsDNA viruses that replicate in the host nucleus poxviruses encode their own replication machinery and therefore replicate in the cytoplasm; viral genes are expressed in a bi-phasic manner with early genes encoding non-structural proteins involved in genome replication and late genes encoding the viral structural proteins

Gene ID

UniProt ID