This product is a made-to-order Monkeypox virus P2L expression plasmid. The product is for research use only and is not approved for use in humans or in clinical diagnosis.
Expression vector or lentiviral vector
Based on vector
Based on specific requirements
Putative alpha aminitin-sensitive protein
MPXVgp024; P2L; putative alpha aminitin-sensitive protein; mutations in this protein may confer resistance to alpha-amanitin, an inhibitor of RNA polymerase II; similar to vaccinia virus strain copenhagen N2L and lumpy skin disease virus 009; The poxviridae are enveloped unsegmented dsDNA viruses; unlike many dsDNA viruses that replicate in the host nucleus poxviruses encode their own replication machinery and therefore replicate in the cytoplasm; viral genes are expressed in a bi-phasic manner with early genes encoding non-structural proteins involved in genome replication and late genes encoding the viral structural proteins