This product is a made-to-order Monkeypox virus O1L expression plasmid. The product is for research use only and is not approved for use in humans or in clinical diagnosis.
Expression vector or lentiviral vector
Based on vector
Based on specific requirements
MPXVgp025; O1L; ankyin-like protein; although the function of the ankyrin-like proteins are not completely understood, they are highly conserved throughout the Orthopoxvirus genus; Ankyrin repeats are tandemly repeated modules of approximately 33 amino acids; there are no known specific sequence or structural motifs which are recognized by the module; the ankyrin-like protein of the modified vaccinia virus ankara interacts with Skp1a, a member of the Skp1a-Cullin-1-F-box (SCF) ubiquitin ligase complex; the poxviridae are enveloped unsegmented dsDNA viruses; unlike many dsDNA viruses that replicate in the host nucleus poxviruses encode their own replication machinery and therefore replicate in the cytoplasm; viral genes are expressed in a bi-phasic manner with early genes encoding non-structural proteins involved in genome replication and late genes encoding the viral structural proteins