This product is a made-to-order Monkeypox virus D1L expression plasmid. The product is for research use only and is not approved for use in humans or in clinical diagnosis.
Expression vector or lentiviral vector
Based on vector
Based on specific requirements
MPXVgp004; ankyrin-like protein; D1L; although the function of the ankyrin-like protein is not completely understood, it is highly conserved throughout the Orthopoxvirus genus; it is composed of ankyrin repeats and an F-box-like domain; it may be critical for overcoming cellular restriction factors; The poxviridae are enveloped unsegmented dsDNA viruses; the ankyrin-like protein of the modified vaccinia virus ankara interacts with Skp1a, a member of the Skp1a-Cullin-1-F-box (SCF) ubiquitin ligase complex; The poxviridae are enveloped unsegmented dsDNA viruses; unlike many dsDNA viruses that replicate in the host nucleus poxviruses encode their own replication machinery and therefore replicate in the cytoplasm; viral genes are expressed in a bi-phasic manner with early genes encoding non-structural proteins involved in genome replication and late genes encoding the viral structural proteins