Anti-Vaccinia Virus A13 Monoclonal Antibody (MP-X7) (Mouse IgG2a/Human IgG1, Kappa)(MPYF-0822-YF7)
This antibody recognizes Vaccinia Virus A13. The isotype is Mouse IgG2a/Human IgG1, Kappa. It can be used in applications: Neut; SPR; WB; ELISA; IF.
Product Description
Species Reactivity
Vaccinia Virus
Cross Reactivity
Orthopoxvirus; Monkeypox Virus; Variola Virus
Specificity
This antibody targets the A13 membrane protein of both the monkeypox and vaccinia viruses. It identifies an epitope consisting of a 10-amino acid sequence that is conserved across all orthopoxviruses, such as monkeypox viruses.
Immunogen
WR strain of live vaccinia virus (VACV)
Antibody Isotype
Mouse IgG2a/Human IgG1, Kappa
Clonality
Monoclonal Antibody
Purification
Protein A affinity purified
Applications
Neut; SPR; WB; ELISA; IF
Application Notes
The antibody was able to identify the 12kda protein in a Western blot of VACV-infected HeLa cells.
Buffer
PBS with 0.02% Proclin 300
Preservative
0.02% Proclin 300
Storage
Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Reference
An epitope conserved in orthopoxvirus A13 envelope protein is the target of neutralizing and protective antibodies.
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Target
Introduction
The Monkeypox virus (MPV) is a zoonotic virus with double-stranded DNA, belonging to the Orthopoxvirus genus in the Poxviridae family. It induces a disease that shares similarities with smallpox, characterized by a milder rash and lower mortality rate. This virus can infect both humans and animals.A13 is crucial for the encapsidation of DNA into immature virions (IV) and the subsequent maturation of these IVs into mature virions (MV).
Alternative Names
VACV; monkeypox virus; Protein P8; A13L; vaccinia virus; smallpox virus; VACV virion membrane proteins; Virion membrane protein A13; VACWR132
Warnings
For Research Use Only. Not for Clinical Use or Diagnostic Use.
Datasheet